Publications
Seeking Recyclable Closure for Paper Beverage Bottles |
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We are seeking technologies for a re-closable fiber-based closure for a paper beverage bottle that can be recycled in the paper stream. |
Seeking Recycling technologies for biodegradable films |
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We are looking for solutions to convert bio-based packaging back to starting materials or other high-value added chemicals (no fuels). |
Seeking existing market solutions targeted towards crawling insects |
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The issue of crawling insects in homes has been an ongoing issue. The popular types of crawling insects causing problems have been ants and cockroaches. The search will focus on existing market solutions targeted towards crawling insects such as ants and cockroaches (other types of crawling insects are in scope i.e., bed bugs). |
Quick RESCUE. New foldable, self-inflating, light and highly portable device for water rescue and lifesaving |
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Ancillary device for water rescue and lifesaving. This small, light device is worn as a waist bag and self-inflates by means of a CO2 cartridge just before making contact with the bather in distress. The device fits snugly around the lifesaver’s waist, generates no resistance for swimming and leaves their hands free in order to carry out preventive lifesaving tasks. Its strong buoyancy once inflated makes it suitable for rescuing heavy or multiple victims. |
Vibration-assisted ball burnishing: A solution for Surface enhancement through acoustoplasticity |
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An innovative system to modify the surface integrity, i.e. surface texture and roughness, hardness and residual stress, of previously milled workpieces has been developed. The system can be easily integrated in real manufacturing environments, but should be tested with that aim. Partners to further develop the system and/or to establish commercial agreements along with technical cooperation are sought. |
Exon skipping by CRISPR-Cas9 editing for Duchenne muscular dystrophy |
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Background Duchenne muscular dystrophy (DMD) is a rare, severe genetic disease characterized by progressive muscle wasting. It is caused by mutations in DMD gene that prevent the production of the muscle isoform of dystrophin protein. The symptom onset is usually in early childhood and life expectancy is ~30 years. Elevidys is currently the only gene therapy approved for DMD, which is designed to deliver a gene coding for a shorter version of dystrophin. This approach was taken because delivery of the whole DMD gene is challenging as it is the largest human gene. Antisense oligonucleotide medications for exon skipping (exons 45, 51, and 53) to produce a shorter yet functional dystrophin gene have been approved, which require periodic administration. None of the drugs is suitable for all DMD patients. More treatment solutions are urgently needed. |
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